Dr Gary Reynolds

Gary Reynolds, Clinical Lecturer at Newcastle University and Specialty Trainee in Rheumatology at the Freeman Hospital

Gary has been awarded a Wellcome Trust Clinical Research Career Development Fellowship for his project examining the role of multinucleated giant cells (MGCs) in GCA. MGCs develop in a range of inflammatory conditions but their functional role is unclear. In this proposal, he intends to apply single cell genomic techniques to understand the transcriptional landscape of GCA-affected temporal artery tissue and use this to validate an in vitro model of MGCs. The aim is to use this model to trial novel therapeutics to target macrophage dysfunction in GCA. The fellowship will last four years starting in mid-2019.