Clinical Studies

PMB Lead: Dr Sarah Mackie, Assistant Professor and Consultant Rheumatologist, University of Leeds and Leeds Teaching Hospitals NHS Foundation Trust

Active Projects

Cohort Studies and Registries

◊ UK GCA Consortium (Professor Ann Morgan; Dr Sarah Mackie)

◊ UKiVAS (Professor Raashid Luqmani)

◊ The GCAT Registry – post-marketing surveillance registry for the use of tocilizumab in the treatment of GCA (Professor Ann Morgan; Dr Mar Pujades Rodriguez; Professor Raashid Luqmani)

Development of Patient-Reported Outcome Measures

◊ A disease-specific patient reported outcome measure for GCA to capture the symptoms and impact on health-related quality of life of the disease and its treatment within clinical trials and clinical care (Dr Jo Robson, Consultant and Senior Lecturer in Rheumatology, University of the West of England, Bristol)

Clinical Assessment

◊ Headache in GCA (Dr Alexandra Sinclair, NIHR Clinician Scientist Fellow and Honorary Consultant Neurologist, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust)

◊ A Bayesian statistical tool for GCA diagnosis (Dr Louis Clearkin, Consultant Ophthalmic Surgeon, Arrowe Park Hospital, Upton, Wirral, SPIRE Murrayfield Hospital, Wirral, and University of Liverpool)

Clinical Trials

◊ The BIOVAS study – biologic agents in non-ANCA vasculitis, including GCA (Dr Pani Gopaluni, Research Fellow, University of Cambridge; Professor David Jayne, Professor of Clinical Autoimmunity, University of Cambridge)

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